Sub remplace()
Application.ScreenUpdating = False
For L = 2 To Range("D65500").End(xlUp).Row
If IsError(Cells(L, "A")) Then
Chaine = Cells(L, "D")
If Asc(Left(Chaine, 1)) = 63 Then Chaine = Mid(Chaine, 2)
Chaine = Replace(Chaine, Chr(10), "")
Chaine = Replace(Chaine, Chr(13), "")
Chaine = LTrim(RTrim(Chaine))
Cells(L, "D") = Chaine
End If
Next L
End Sub